Your Premiere Oxford Dentist

Providing the Highest Quality Care to Patients of all Ages

Since 2004, Dr. John Khoury and his dedicated team have provided top-notch dental care to the Oxford community. At our convenient location at 1120 South Lapeer Road, we offer family and cosmetic dentistry for all ages. Our clinic features the latest technology, ensuring every patient receives the highest standard of care. Under the guidance of a compassionate and skilled Oxford dentist, we are committed to helping you achieve and maintain optimal dental health.

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At our office, we use clinical laboratory services from OralDNA Labs® to ensure we are giving our patients the best oral health information possible. OralDNA Labs® is a specialty diagnostics company designed to provide reliable, definitive and cost effective clinical tests that guide oral health professionals in detecting and prognosing disease at an earlier, more treatable stage.

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Experienced Team

Dr. John Khoury and staff are dedicated to providing service that is friendly and professional. Every member of our team has at least several years of experience in both family dentistry and cosmetic dentistry. We are passionate about patient care. We'll work hard to give you something to smile about.


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  Meet Dr. John Khoury

After earning his Bachelor of Science degree from Western Michigan University, Dr. John Khoury completed his Doctor of Dental Surgery at the University of Detroit Mercy School of Dentistry. Dr. Khoury opened John Khoury Dental (formerly the Oxford Smile Center) in August 2004 with the mission of serving the community where he has lived his entire life.

Dr. Khoury believes in professional growth and development and with advanced clinical training, experience, and education, he will provide the finest care available through modern dentistry. He is currently in an advanced curriculum at Spear Education in Scottsdale, AZ to learn the latest and most advanced techniques.

Dr. Khoury is dedicated to ensuring that care is delivered in the most comfortable manner possible. He believes in co-creating a plan with you that is aimed toward your personal goals for health, beauty, function, and quality of life and his clinical goals for stability, precision, and longevity.

We Create an Enjoyable Experience

Our goal is to make your visit comfortable from the start. Comfort starts with trust. We work to build your trust in our services and knowledge. In our experience, dental fear or phobia comes from a place of distrust. We have found patients that are very nervous to start eventually get very comfortable with dental treatment knowing that we will tell them everything they need to know and that we have their best interest at heart.

We provide a range of extras to help make the experience more comfortable and safer. We offer simple things like back and neck pillows all the way to oral conscious sedation. Click here to learn more about our services to make your experience better.


See Us in the Community

We believe strongly in giving back to the community. Dr. Khoury and staff sponsor many different activities in the Oxford/Lake Orion community. The office sponsors many different local sports programs, as well as donating needed oral hygiene supplies to different programs. Dr. Khoury is a volunteer with Donated Dental Services which provides free dental care to those in need. Dr Khoury is an active parishioner at St. Joseph’s Church in Lake Orion. The office hosts a Halloween Candy Buy Back every year. The event gets nearly 500 lbs. of candy annually. The candy is donated to the American Legion in Oxford, which then send it over to the troops. Dr Khoury believes one of the keys to leading a happy and healthy life is supporting others and giving back.

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Our Office

What Our Patients Are Saying

  • I could feel the effects of grinding and the loss of functionality, and it concerned me.
    Socially, I didn’t think it really affected my self-confidence. Though, now that I have completed treatment, I do find it easier to approach people. I could see the results of nightly grinding and it wasn’t going to get better without action on my part. I made the decision to set a dental goal for myself and together Dr. Khoury and I came up with a plan. I rarely visited the dentist prior to this decision so having regular visits was a huge change to overcome. My dental health, self-esteem and social interaction have all been improved. People are nicer to me, even strangers. Now that my bite is fixed, I am more confident when eating in public because of cleanliness.

    Kyle C.
  • Just had my teeth cleaned and it was great! The hygienist was thorough as well as gentle. I always have a lot of plaque in front on my lower teeth and it's a sensitive area. The hygienist was mindful of how much it could hurt.

    Jean C.
  • What a wonderful surprise I had when I visited Dr. Khoury and his staff at Oxfrord Smile Center to have my 6 front teeth prepped for a makeover. Having been to several non-empathetic dentists lacking care or competency, I felt deep appreciation for this exceptionally gifted dentist and talented staff. From start to finish, I never felt a single twinge of pain or discomfort. His procedure was focused and deliberate, and his staff assisted with exceptional skill. I am in my senior years and approached this venture with great apprehension. I am convinced it was the right decision. I have great trust for this group.

    Pamela K.
  • Everyone has something they feel they want in their life, but are not sure they can attain it. Mine was a bright, big white smile. As people age, teeth continue to yellow, spaces get bigger and general health of teeth deteriorates. Top on my bucket list was a new smile, and The Oxford Smile Center helped me realized this important wish. I am so happy with my smile, and Dr. Khoury, Brenda, Andrea and the entire staff made sure it was just what I asked for. Amazingly, the color is perfect, and it doesn't look like I have "false teeth". Remnants of little imperfections in the shape of my teeth that gave me my own personality are still there - just enough so I know these teeth are still mine.

    Pamela K.
  • Dr. Khoury and all of the staff are incredibly personable and skilled. Really nice to walk through the door with a sense of trust to be in the hands of such incredible people.

    John R.